Stanic lab is focused on deciphering the role of Innate Lymphoid cells and immune cellular networks in the architectural organization of the maternal/fetal interface.
Dr. Stanic's research program is dedicated to unravelling the cellular networks underlying preeclampsia, intrauterine growth restriction, recurrent pregnancy loss and implantation failure in Assisted Reproductive Technologies.
Our lab employs both human and mouse models of reproductive physiology and disease. We use genetic targeting of immune cell development and function to dissect their role in reproductive tissue organization and disease. We collaborate closely with biostatisticians and computer scientists to develop novel workflows for analysis of our high-dimensional flow cytometry data sets and model the reproductive immune cell network.
Dr. Aleksandar Stanic is an assistant professor in the University of Wisconsin-Madison Department of Obstetrics and Gynecology, divisions of Reproductive Sciences and Reproductive Endocrinology and Infertility.View Biosketch
Read more about Dr. Stanic
I was born in China, and finished my medical school in 2005, then I worked as a resident of Ob/Gynthe third affiliated hospital of Jiangxi medical school in China until 2008. I attended the Dept of Ob/Gyn in University of Wisconsin-Madison as a research assistant in 2009 to pursuit my PhD degree. I finished my PhD study on July,2015. After that, I joined in Dr. Stanic's lab as aresearchassociate in the department of Ob/Gyn in University ofWisconsin.Read more about Yan
I was born and raised in Los Angeles, California. I completed by undergraduate degree at California State University, Long Beach. After a year hiatus, I decided to go back to school, went back to my alma mater, were I completed a post-bacc certificate. From there, I went on to receive my Masters from California State University, Los Angeles and I am currently working towards my PhD in the Endocrinology and Reproductive Physiology program at UW-Madison.Read more about Jessica
I was born in Bogota, Colombia. Got my Bachelor degree in Chemistry at the Universidad Nacional de Colombia. Thanks to a scholarship from the Colombian Government, I came to the United States to get my Master degree in Biochemistry at the University of New Hampshire. Since then I have been working in basic research.Read more about Gladys
I was born and raised in Los Angeles, CA. I graduated from high school in the spring of 2015. In the fall of 2015, funded by a full tuition leadership scholarship, I moved to Madison to complete my Bachelor's degree in Biology at the University of Wisconsin-Madison. This year, will be my third year at UW-Madison. My plans are to graduate in the fall of 2019 and start medical school in the fall of 2020.Read more about Melina
I am currently an undergraduate student at the University of Wisconsin-Madison studying biology and dietetics. After graduation, I plan on attending medical school and specializing in the fields of obstetrics and gynecology or pediatrics. Outside of academics, I have a wonderful job as a personal trainer on campus. Along with personal training, I live a fitness oriented lifestyle with my hobbies that include weightlifting and spending time outdoors.Read more about Nathan
I am an undergraduate student at University of Wisconsin Madison, majoring in Biology with a certificate in global health. I am originally from a suburb of Chicago, which is what drew me to the big city feel of Madison. In my spare time I like to spend time in the sun, waitress, run and attend concerts. After I graduate from UW Madison, I will start applying to Medical/DO schools that are (hopefully) somewhere warm. Women’s health is very important to me, which is why I was so interested in this labs work.Read more about Jenna
I was born in Massachusetts andmoved toIllinoiswhen I was five.In 2016, I began my undergraduate education at the University of Wisconsin, Madison. I am pursuing a major in Microbiologywhich I plan to apply to the field of Immunology. Other hobbies include playing the tuba in the marching band, studyingancient and classic literature, and attending a variety of performing arts.Read more about Luke
I was born and raised on a crop farm in Wisconsin Dells, WI. I am obtaining my undergraduate degrees from the University of Wisconsin - Madison in Biology and Classical Humanities. I work at UW- Hospital as a phlebotomist and thoroughly enjoy patient care. I plan to go to medical school to get my MD in a field that involves children (hopefully Obstetrics). In my free time I love doing hot yoga, long-distance running, knitting, and I enjoy the company of my friends and family. Lastly, go Badgers, go Packers, go Brewers.Read more about Payton
Decidual-Placental Immune Landscape During Syngeneic Murine Pregnancy.
Li Y, Lopez GE, Vazquez J, Sun Y, Chavarria M, Lindner PN, Fredrickson S, Karst N, Stanic AK. Frontiers in immunology. 2018 Sep 19. pii: . 10.3389/fimmu.2018.02087. PMID: 302834412018/10/05 06:00.
NF-κB Protects NKT Cells from Tumor Necrosis Factor Receptor 1-induced Death.
Kumar A, Gordy LE, Bezbradica JS, Stanic AK, Hill TM, Boothby MR, Van Kaer L, Joyce S. Scientific reports. 2017 Nov 15. pii: 10.1038/s41598-017-15461-y. 10.1038/s41598-017-15461-y. PMID: 291422752017/11/17 06:00.
Computational flow cytometry analysis reveals a unique immune signature of the human maternal-fetal interface.
Vazquez J, Chavarria M, Li Y, Lopez GE, Stanic AK. American journal of reproductive immunology (New York, N.Y. : 1989). 2017 Oct 14. pii: . 10.1111/aji.12774. PMID: 290309002017/10/17 06:00.
Characterization and Functional Analysis of Mouse Semi-invariant Natural T Cells.
Kumar A, Bezbradica JS, Stanic AK, Joyce S. Current protocols in immunology. 2017 Apr 3. pii: . 10.1002/cpim.22. PMID: 283696822017/04/04 06:00.
Association between peak estradiol levels and ovarian torsion among symptomatic patients receiving gonadotropin treatment.
Romanski PA, Melamed A, Elias KM, Stanic AK, Anchan RM. Journal of assisted reproduction and genetics. 2017 Mar 15. pii: 10.1007/s10815-017-0901-y. 10.1007/s10815-017-0901-y. PMID: 282995502017/03/17 06:00.
View All Publications on PubMed
5 K12 HD 000849-28 (Program PI: K. Moley) 07/01/2013 – 06/30/2018
NIH/NICHD Reproductive Scientist Development Program (RSDP)
Project Role: Scholar
Title: The role of Innate Lymphoid Cells in Decidual Function
The goal of this project is to determine the role Innate Lymphoid Cells play in decidual vascular remodeling necessary for healthy placenta and pregnancy. Phase I – current – 2 years, Phase 2 – renewal – 3 years.
RSDP Research Support
Burroughs Wellcome Fund (BWF) 07/01/2016 – 06/30/2018
Funding associated with Dr. Stanic’s role as a Phase I RSDP Scholar
RSDP Research Supplement
March of Dimes (MOD) 07/01/2016 – 06/30/2017
Supplement to funding associated with Dr. Stanic’s role as a Phase I RSDP Scholar
AAI Careers in Immunology Fellowship
American Association of Immunologists – 09/01/2016 – 08/31/2017
Project Role: PI (Stanic) Funded fellow: Dr. Yan Li
Funding for AAI Trainee member (Dr. Li) postdoctoral salary in the laboratory of AAI Regular Member (Dr. Stanic). Title: Innate Lymphoid Cell – Dendritic Cell Axis Regulates Vascular Remodeling at the Maternal-Fetal Interface.
Stanic Lab News
An article in the American Journal of Reproductive Immunology was co-authored by researchers in the UW Ob-Gyn Divisions of Reproductive Sciences and Gynecologic Oncology!
“Identification of … more
Congratulations to Aleks Stanic-Kostic, MD, PhD, of the UW Ob-Gyn Divisions of Reproductive Endocrinology and Infertility and Reproductive Sciences! Stanic was invited to serve on a new task force … more
Members of the UW Ob-Gyn Division of Reproductive Science’s Stanic Lab published the manuscript “The role of RORγt at maternal‐fetal interface during Murine Pregnancy” in the American Journal of … more
Congratulations to the Stanic Lab, along with colleagues from the Division of Maternal-Fetal Medicine and the Ong Lab, who were just published in the journal Frontiers in Immunology!
“ … more
On December 10, 2019, four UW-Madison undergraduate students with UW Ob-Gyn faculty mentors presented research posters at the Introductory Biology 152 Undergraduate Research Poster Session. … more
UW Ob-Gyn’s resident Reproductive Scientist Development Program scholar Aleks Stanic, MD PhD, recently earned an additional grant from the program to support his research!
This latest RSDP … more
A few exciting updates from the always-prolific Aleks Stanic, MD PhD, of the UW Ob-Gyn Divisions of Reproductive Sciences and Reproductive Endocrinology and Infertility, as well as others in his … more
On June 20, the UW Department of Ob-Gyn celebrated faculty, residents, staff and more at our annual department awards ceremony. Congratulations to the 2019 winners!
Residency Program Awards
Chief … more
Congratulations to Irene Ong, PhD, of the UW Ob-Gyn Division of Reproductive Sciences, Aleks Stanic, MD PhD, of Reproductive Sciences and the Division of Reproductive Endocrinology and Infertility, … more
On Friday, May 10, three students in the Endocrinology and Reproductive Physiology Program with UW Ob-Gyn mentors graduated! Congratulations to these newly minted PhDs:
Yousef Alharbi, PhD – … more
Huge congratulations to three UW Ob-Gyn physicians who passed their American Board of Obstetrics and Gynecology subspecialty exams with flying colors this week!
Laura Cooney, MD, of the UW Ob- … more
Congratulations to many members of the UW Ob-Gyn Division of Reproductive Sciences, who represented the department at the 66th annual Society for Reproductive Investigation (SRI) meeting in Paris … more
Huge congratulations to Aleks Stanic, MD, PhD, of the UW Ob-Gyn Divisions of Reproductive Endocrinology and Infertility and Reproductive Sciences! Stanic is one of a few recipients of the new … more