Download Dave Abbott's BioSketch
to read about Dr. Abbott's accomplishments: including positions, honors, awards, selected peer-reviewed publications, research support and scholarly activity.
- BSc 1975 University of Endinburgh, Edinburgh, Scotland
- PhD 1979 University of Edinburgh, Edinburgh, Scotland
- 1st Postdoctoral Position: University of Wisconsin-Madison
I have over 30 years of experience employing animal models of female reproductive endocrinology to determine pathophysiological mechanisms underlying a variety of reproductive health disorders commonly found in women. More recently, in collaboration with Dr. Dumesic (Co-I in this application), my lab developed a comprehensive nonhuman primate model for polycystic ovary syndrome (PCOS) that was the vanguard for a multitude of animal and human studies aimed at determining developmental origins of this most common endocrinopathy in women. We have translated insight gained from the nonhuman primate model to discern pathophysiological mechanism causing discrete aspects of reproductive and metabolic dysfunction in women with PCOS, including abnormalities at the molecular level. Our most recent work identifies metabolic dysfunction as possibly the initial abnormality in early developmental origins of PCOS.