Abbott and co-authors publish in Seminars in Reproductive Medicine

David Abbott, PhD, professor in the Division of Reproductive Sciences, recently co-authored a new article published in Seminars in Reproductive Medicine. Co-authors include Beverly Hutcherson and Daniel Dumesic.

In “Anti-Mullerian Hormone: A Molecular Key to Unlocking Polycystic Ovary Syndrome?,” Abbott and co-authors evaluated the correlation between hormone levels and PCOS symptoms in hyperandrogenic (HA) female rhesus monkeys. They specifically focussed on testosterone and anti-mullerian hormones (AMH), finding that:

“Gestational or peripubertal exogenous T or dihydrotestosterone induction of PCOS-like traits in female mice, rats, sheep, and monkeys fails to elicit ovarian AMH hypersecretion; thus, AMH excess per se may lead to a distinct pathogenic contribution to hyperandrogenic PCOS origins.”

Read the full article here.

**by Ob-Gyn Communications Intern Paige Stevenson