Department of
Obstetrics and Gynecology

UNIVERSITY OF WISCONSIN–MADISON
SCHOOL OF MEDICINE AND PUBLIC HEALTH

Division of Reproductive Sciences

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We are often asked, “Why conduct and invest in basic research in a clinical department?” An investment in basic research at the cellular and molecular level provides us with the tools needed to understand diseases that do not yet have a clinical treatment. Where therapies are known and have complications, basic science research is essential to understanding their side effects and how to avoid them.

A significant focus of our basic research program is in seeking to understand the cellular and molecular interactions and functions that are needed to establish a healthy pregnancy to full gestation in both animal and human models. A healthy pregnancy has the greatest benefit to mother, child and society; however, understanding the causes of pregnancy complications such as pre-eclampsia and potential pre-term labor and delivery that result from this condition is essential to developing safe, effective treatments for mother and child.

Our Mission

As an academic institution, our mission is to educate future scientists and physicians in the new world of interdisciplinary and collaborative biomedical research. In particular, for NIH’s (National Institutes of Health) initiative to build interdisciplinary teams to be achieved we must have basic researchers working in clinical departments in order to understand what the clinical problem is at a mechanistic level. Likewise for doctors who are practicing clinical medicine to know what is possible they need to see and understand cutting edge research being done in their own department. We must not overlook the pre- and post-doctoral scholars within our department who are essential to advancing the research mission not only to support work conducted by the faculty Principal Investigator, but also to develop their own career paths through guided mentorship and training. For these reasons, conducting basic research in a clinical department is essential to a healthy and bright future for all women, infants and children.

 Abbott published in Reproductive Biology and Endocrinology

Abbott published in Reproductive Biology and Endocrinology

A new article by David Abbott, PhD, of the UW Ob-Gyn Division of Reproductive Sciences, examines historical evidence that polycystic ovary syndrome (PCOS) may have originated as an evolutionary adaptation for reproduction during food scarcity.“Polycystic ovary syndrome as a plausible evolutionary outcome of metabolic adaptati... more
 Stanic Lab published in American Journal of Reproductive Immunology

Stanic Lab published in American Journal of Reproductive Immunology

A new article out of collaborative research between Aleks Stanic-Kostic, MD, PhD and Irene Ong, PhD was published in the American Journal of Reproductive Immunology!“Multiomic analysis reveals decidual-specific transcriptional programing of MAIT cells” examines the possible role of Mucosal-Associated Invariant T (MAIT) cells ... more
 Ong’s work on AyrFlo intervention featured in Madison Magazine

Ong’s work on AyrFlo intervention featured in Madison Magazine

Over the last few years, Irene Ong, PhD, of the UW Ob-Gyn Division of Reproductive Sciences, has been working with clinician-scientists in the SMPH Departments of Anesthesiology and Radiology to develop a device that could identify respiratory distress earlier.An article in the November 2021 issue of Madison Magazine introduc... more

Abbott mentees present at Biology 152 Research Symposium

Undergraduate students mentored by David Abbott, PhD, of the UW Ob-Gyn Division of Reproductive Sciences, shared their research projects at the UW-Madison Biology 152 Research Symposium on December 14, 2021!Mihika Sathe brought a poster on excess fetal testosterone exposure in male rhesus monkeys and how it induces pancreatic... more

Grand Rounds: Badger Bytes on PCOS

On December 2, 2021, three presenters offered different updates on PCOS during the UW Ob-Gyn Grand Rounds Badger Bytes research presentation. David Abbott, PhD, of the UW Ob-Gyn Division of Reproductive Sciences, Laura Cooney, MD, of the Division of Reproductive Endocrinology and Infertility, and Leeann Bui, UW SMPH medical s... more