Hoppe co-authors two articles about CHAP Trial outcomes in Green Journal

Kara Hoppe, DO, MS, associate professor  in the Division of Maternal-Fetal Medicine and Vice Chair of Clinical Research, recently co-authored two articles published in Obstetrics and Gynecology.

In “Pregnancy Outcomes of Nifedipine Compared With Labetalol for Oral Treatment of Mild Chronic Hypertension,” co-authors compared the maternal and neonatal outcomes for different antihypertensives for participants in the CHAP (Chronic Hypertension in Pregnancy) trial.

Their research found “there were no significant differences in SGA (small for gestational age neonates) or serious adverse events between participants receiving labetalol and those receiving nifedipine.”

Read the whole article here.

In the corresponding article, “Mean Arterial Pressure and Neonatal Outcomes in Pregnancies Complicated by Mild Chronic Hypertension,” co-authors sought to find an association between mean arterial pressure during pregnancy and neonatal outcomes for patients with chronic hypertension that also were involved in the CHAP trial.

Co-authors found that “increasing average mean arterial pressure per millimeter of mercury was associated with an increase in each neonatal outcome examined except NEC, specifically neonatal composite.”

You can read the full article here.