Ong co-authors new article about radiation therapy

Irene Ong, PhD, associate professor in the Division of Reproductive Sciences, co-authored a new study in Science Translational Medicine about mixed-dose radiation.

In Intratumoral radiation dose heterogeneity augments antitumor immunity in mice and primes responses to checkpoint blockade, Ong and co-authors studied the impacts of combined high and low-dose radiation on tumors in mice, finding that:

“…this heterogeneous approach outperformed homogeneous dose RT in a T cell–dependent manner and could be combined with immune checkpoint inhibition. These data support further clinical development of heterogeneous RT.”

The UW School of Medicine and Public Health shared an article highlighting the study and its potential implications. You can read the article in Science Translational Medicine here, and find the UW SMPH research article about the study here. Incredible work, Dr. Ong!