Kathleen Antony, MD, MSCI
Associate Professor (CHS)
UnityPoint Health-MeriterUniversity of Wisconsin Hospital
As a maternal-fetal medicine specialist with a 70% clinical commitment, I have focused my academic efforts on obesity in the context of pregnancy. Obesity is the most common comorbidity of pregnancy and affects over half of all women who deliver at Meriter Hospital. Obesity increases the risk of many adverse pregnancy outcomes including sleep apnea and the risk of respiratory depression after surgeries, among many others.
As a resident physician, I performed a prospective observational study of 1600 pregnant women on obstructive sleep apnea during pregnancy. As a fellow, I investigated the effect of obesity and gestational weight gain on the placental microbiome. As a new faculty member, I spearheaded several obesity-related projects.
The overarching theme of my clinical and research endeavors is to improve the peripartum care of pregnant women with obesity. Over the last five years, I have developed a regional reputation regarding research, education, and clinical expertise on obesity and pregnancy.
My current research interests include the following:
-Obesity during pregnancy and the peripartum time period
-Optimizing the care of pregnant women with obesity from the antepartum through the postpartum time period
-Optimizing pain control of women in the peripartum time period
-Reducing surgical site infections following cesarean birth
|2004||B.S.||Chemistry and Biology, Washington University in St. Louis, St. Louis, MO|
|2008||M.D.||University of Rochester School of Medicine, Rochester, NY|
|2012||Residency||Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX|
|2015||Fellowship||Maternal-Fetal Medicine, Baylor College of Medicine, Houston, TX|
|2015||Masters||Clinical Investigation, Baylor College of Medicine, Houston, TX|
Diplomate, American Board of Obstetrics and Gynecology
Subspecialty Certification in Maternal-Fetal Medicine, American Board of Obstetrics and Gynecology
Diplomate, American Board of Obesity Medicine
University of Wisconsin School of Medicine and Public Health, Department of Obstetrics and Gynecology, Grand Rounds Liaison and Facilitator (05/2018 – 07/2020)
University of Wisconsin School of Medicine and Public Health, Department of Obstetrics and Gynecology, Residency Research Program Faculty Advisor (04/2016-present)
Wisconsin ACOG Representative to the Wisconsin Counsel on Immunization Practices (06/2017-present)
Director of Inpatient Safety and Quality, Unity-Point Meriter Hospital, Center for Perinatal Care, Madison, WI (08/2018-Present)
University of Wisconsin School of Medicine and Public Health, Department of Obstetrics and Gynecology, Resident Research Program Director (06/2020-Present)
Ben Taub General Hospital, Harris Health System, Houston, TX, 2008-2015 (Residency, Fellowship)
Texas Children’s Hospital Pavilion for Women, Houston, TX, 2008-2015 (Residency, Fellowship)
Women’s Hospital of Texas, Houston, TX, 2009-2012 (Residency)
St. Luke’s Episcopal Hospital, Houston, TX, 2010-2012 (Residency)
Michael E. DeBakey Veteran’s Affairs Medical Center, Houston, TX, 2011-2012 (Residency)
Meriter Hospital, UnityPoint Health System, Madison, WI, 2015-present
UW Hospital and Clinics, UW Health System, Madison, WI, 2015-present
Baylor College of Medicine Department of Obstetrics and Gynecology Resident Research Grant 2011-2012
Raymond H. Kaufman, M.D. Resident Mentor Award, 2012
American Academy of Pediatrics, 82nd Perinatal and Developmental Medicine Symposium, Travel Award, 2013
Committee Member, Faculty Development Steering Committee, Department of Obstetrics and Gynecology, University of Wisconsin School of Medicine and Public Health, October 2015-October 2018.
Committee Member, Obesity Clinical Taskforce, Department of Obstetrics and Gynecology, University of Wisconsin School of Medicine and Public Health, September 2016-2019.
Committee Member, Obesity Research Taskforce, Department of Obstetrics and Gynecology, University of Wisconsin School of Medicine and Public Health, September 2016-2019.
Committee Member, Obesity in Pregnancy Workgroup, UnityPoint Health – Meriter Hospital, November 2016-2018.
Committee Member, Quality Improvement Review Committee (QIRC), Department of Obstetrics and Gynecology, University of Wisconsin School of Medicine and Public Health, May 2018-Present.
Committee Member, Placental Pathology Ad Hoc Committee. University of Wisconsin School of Medicine and Public Health, September 2018-Present
Co-chair, Obstetrical Enhanced Recovery After Surgery Committee, UnityPoint Health-Meriter Hospital, January 2020-Present.
Sigma Xi (Chemistry Honor Society),
Washington University in St. Louis
Phi Beta Kappa,
Washington University in St. Louis
American College of Obstetricians and Gynecologists
Society for Maternal-Fetal Medicine
American Board of Obstetrics and Gynecology
Talia C Oughourlian, Guistinna Tun, Kevin M Antony, Arpana Gupta, Vickie M Mays, Emeran A Mayer, Andrea J Rapkin, Jennifer S Labus
Published Date: August, 2022 - pmid:35972459 - Pain
Lauren E Raasch, Keisuke Yamamoto, Christina M Newman, Jenna R Rosinski, Phoenix M Shepherd, Elaina Razo, Chelsea M Crooks, Mason I Bliss, Meghan E Breitbach, Emily L Sneed, Andrea M Weiler, Xiankun Zeng, Kevin K Noguchi, Terry K Morgan, Nicole A Fuhler, Ellie K Bohm, Alexandra J Alberts, Samantha J Havlicek, Sabrina Kabakov, Ann M Mitzey, Kathleen M Antony, Karla K Ausderau, Andres Mejia, Puja Basu, Heather A Simmons, Jens C Eickhoff, Matthew T Aliota, Emma L Mohr, Thomas C Friedrich, Thaddeus G Golos, David H O'Connor, Dawn M Dudley
Published Date: August, 2022 - pmid:35926066 - PLoS neglected tropical diseases
Jeannette M Larson, Mihaela H Bazalakova, Amy Godecker, Melanie DelBeccaro, Kjersti M Aagaard, Kathleen M Antony
Published Date: August, 2022 - pmid:35925932 - PloS one
Dawn M Dudley, Michelle R Koenig, Laurel M Stewart, Matthew R Semler, Christina M Newman, Phoenix M Shepherd, Keisuke Yamamoto, Meghan E Breitbach, Michele Schotzko, Sarah Kohn, Kathleen M Antony, Hongyu Qiu, Priyadarshini Tunga, Deborah M Anderson, Wendi Guo, Maria Dennis, Tulika Singh, Sierra Rybarczyk, Andrea M Weiler, Elaina Razo, Ann Mitzey, Xiankun Zeng, Jens C Eickhoff, Emma L Mohr, Heather A Simmons, Michael K Fritsch, Andres Mejia, Matthew T Aliota, Thomas C Friedrich, Thaddeus G Golos, Shantha Kodihalli, Sallie R Permar, David H O'Connor
Published Date: July, 2022 - pmid:35834540 - PloS one
Alexandra Lauren Rice, Sakshi Bajaj, Abigail M Wiedmer, Natalie Jacobson, Aleksandar K Stanic, Kathleen M Antony, Mihaela H Bazalakova
Published Date: June, 2022 - pmid:35750926 - Sleep & breathing = Schlaf & Atmung
Ingmar N Bastian, Kathleen M Antony
Published Date: March, 2022 - pmid:35339017 - Pregnancy hypertension
Courtney Johnston, Amy Godecker, Daniel Shirley, Kathleen M Antony
Published Date: March, 2022 - pmid:35281850 - Infectious diseases in obstetrics and gynecology
Jacquelyn H Adams, John Poehlmann, Jenna L Racine, J Igor Iruretagoyena, April Eddy, Kara K Hoppe, Katharina Stewart, Janine Rhoades, Kathleen M Antony
Published Date: March, 2022 - pmid:35272547 - The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
John R Poehlmann, Zachary N Stowe, Amy Godecker, Pa Ta Xiong, Aimee Teo Broman, Kathleen M Antony
Published Date: February, 2022 - pmid:35114423 - American journal of obstetrics & gynecology MFM
Jessica L Walker, Jacquelyn H Adams, Aimee T Broman, Peter G Pryde, Kathleen M Antony
Published Date: January, 2022 - pmid:35036046 - AJP reports
Pa Ta Xiong, John Poehlmann, Zachary Stowe, Kathleen M Antony
Published Date: December, 2021 - pmid:34854926 - Obstetrical & gynecological survey
Karla Ausderau, Sabrina Kabakov, Elaina Razo, Ann M Mitzey, Kathryn M Bach, Chelsea M Crooks, Natalie Dulaney, Logan Keding, Cristhian Salas-Quinchucua, Lex G Medina-Magües, Andrea M Weiler, Mason Bliss, Jens Eickhoff, Heather A Simmons, Andres Mejia, Kathleen M Antony, Terry Morgan, Saverio Capuano, Mary L Schneider, Matthew T Aliota, Thomas C Friedrich, David H O'Connor, Thaddeus G Golos, Emma L Mohr
Published Date: September, 2021 - pmid:34578459 - Viruses
Ruolin Song, Jay S Mishra, Sri Vidya Dangudubiyyam, Kathleen M Antony, Tracy L Baker, Jyoti J Watters, Sathish Kumar
Published Date: September, 2021 - pmid:34550599 - Reproductive sciences (Thousand Oaks, Calif.)
Melissa F Meyer, Aimee T Broman, Sarah E Gnadt, Shefaali Sharma, Kathleen M Antony
Published Date: August, 2021 - pmid:34445918 - The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Chelsea M Crooks, Andrea M Weiler, Sierra L Rybarczyk, Mason I Bliss, Anna S Jaeger, Megan E Murphy, Heather A Simmons, Andres Mejia, Michael K Fritsch, Jennifer M Hayes, Jens C Eickhoff, Ann M Mitzey, Elaina Razo, Katarina M Braun, Elizabeth A Brown, Keisuke Yamamoto, Phoenix M Shepherd, Amber Possell, Kara Weaver, Kathleen M Antony, Terry K Morgan, Christina M Newman, Dawn M Dudley, Nancy Schultz-Darken, Eric Peterson, Leah C Katzelnick, Angel Balmaseda, Eva Harris, David H O'Connor, Emma L Mohr, Thaddeus G Golos, Thomas C Friedrich, Matthew T Aliota
Published Date: July, 2021 - pmid:34329306 - PLoS neglected tropical diseases
Gordon GH, Berdahl DM, Hoppe KK, Antony KM. “The use of sildenafil in severe early-onset fetal growth restriction: a case report and review of current literature.” Frontiers in Women’s Health. 2018 Jun 11: 3(3): 1-4. doi: 10.15761/FWH.1000147
Chu D, Ma J, Prince A, Antony K, Seferovic M, Aagaard K. “Maturation of the infant microbiome community structure and function across multiple body sites and in relation to mode of delivery.” Nature Medicine. 2017 Mar;23(3):314-326. PMID: 28112736
Antony KM, Ehrenthal D, Evensen A, Iruretagoyena JI. “Travel During Pregnancy: Considerations for the Obstetric Provider.” Obstetrical & Gynecological Survey. 2017 Feb;72(2):97-115. PMID: 28218771
Antony KM, Hemarajata P, Chen J, Morris J, Cook C, Masalas D, Gedminas M, Brown A, Versalovic J, Aagaard K. “Generation and validation of a universal perinatal database and biospecimen repository: PeriBank.” Journal of Perinatology. 2016 Nov; 36(11):921-929. PMID: 27629376
Chabarria KC, Racusin DA, Antony KM, Kahr M, Suter MA, Mastrobattista JM, Aagaard KM. “Marijuana Use and its Effects in Pregnancy.” American Journal of Obstetrics and Gynecology. 2016 Oct; 215(4):506.e1-7. PMID: 27263998
Chu DM, Antony KM, Ma J, Prince AL, Showalter L, Moller M, Aagaard KM. “The early infant gut microbiome varies in association with a maternal high-fat diet.” Genome Medicine. 2016 Aug 9; 8(1):77. PMID: 27503374
Racusin DA, Antony KM, Haase J, Bondy M, Aagaard KM. “Mode of delivery in Premature Neonates: Does it Matter?” American Journal of Perinatology Reports. 2016 Jul;6(3):e251-9. PMID: 27468363
Kahr MK, Antony KM, DelBeccaro M, Hu M, Aagaard KM, Suter MA. “Increasing Maternal Obesity is Associated with Alterations in both Maternal and Neonatal Thyroid Hormone Levels.” Clinical Endocrinology. 2016 Apr;84(4):551-7. PMID: 26562744
Racusin DA, Villarreal S, Antony KM, Harris RA, Mastrobattista J, Wesley L, Shamshirsaz A, Belfort M, Aagaard KM. “The Role of MSAFP and Ultrasonography in Contemporary Detection of Spina Bifida.” American Journal of Perinatology. 2015 Dec; 3(14):1287-91. PMID: 26332586
Antony KM, Ma J, Mitchell KB, Racusin DA, Versalovic J, Aagaard K. “The Preterm Placental Microbiome Varies in Association with Excess Maternal Gestational Weight Gain.” American Journal of Obstetrics and Gynecology. 2015 May; 212(5):653.e1-16. PMID: 25557210
Antony KM, Mansouri R, Arndt M, Hui SR, Jariwala P, Moreland McMullen V, Teruya J, Aagaard KM. “Establishing Thromboelastography with Platelet-Function Analyzer Reference Ranges and Other Measures in Healthy Term Pregnant Women.” American Journal of Perinatology. 2015 May; 32(6):545-54. PMID: 25594216
Racusin DA, Antony KM, Showalter LA, Sharma S, Haymond MW, Aagaard KM. “Candy twists as an alternative to the glucola beverage in gestational diabetes screening.” American Journal of Obstetrics & Gynecology. 2015 Apr; 212(4):522.e1-5. PMID: 25446695
Prince AL, Chu DM, Seferovic MD, Antony KM, Ma J, Aagaard. “The Perinatal Microbiome and Pregnancy: Moving Beyond the Vaginal Microbiome.” Cold Spring Harbor Perspectives in Medicine. 2015 Mar 16; (5)6. PMID: 25775922
Prince AL, Antony KM, Chu DM, Aagaard KM. “The Microbiome, Parturition, and Timing of Birth: More questions than answers.” Journal of Reproductive Immunology. 2014 Oct; 104-105:12-9. PMID: 24793619
Antony KM, Agrawal A, Arndt M, Murphy A, Alapat P, Guntupalli K, Aagaard K. “Obstructive Sleep Apnea in Pregnancy: Reliability of Prevalence and Prediction Estimates.” Journal of Perinatology. 2014 Aug;34(8):587-93. PMID: 24674980
Antony KM, Agrawal A, Arndt M, Murphy A, Alapat P, Guntupalli K, Aagaard K. “Association of Adverse Perinatal Outcomes with Screening Measures of Obstructive Sleep Apnea.” Journal of Perinatology. 2014 Jun;34(6):441-8. PMID: 24603455
Aagaard K, Ma J, Antony K, Ganu R, Petrosino J, Versalovic J. “The Placenta Harbors a Unique Microbiome.” Science Translational Medicine. 2014 May 21;6(237)237ra65. PMID: 24848255
Prince A, Antony KM, Aagaard KM. “The Microbiome and Development: A Mother’s Perspective.” Seminars in Reproduction. 2014 Jan;32(1):14-22. PMID: 24390916
My Roles: Co-PI with Dr. Mihaela Bazalakova
Research Focus: Sleep apnea during pregnancy: evaluation of referral process, assessment of screening tools, development of new tools, and evaluation of obstetric outcomes
The purpose of this study is multi-fold. The overarching goal is to harness the database of women referred for sleep apnea screening that we created for quality improvement purposes to further improve the quality of care for pregnant women who may have sleep apnea. However, we also seek to compare groups of women and analyze the questionnaires to develop a more optimal screening tool.
Sponsor(s): Department of Obstetrics and Gynecology: Startup Funds
My Roles: PI
Research Focus: To determine whether 5% lidocaine patches placed around the skin incision following Cesarean delivery will reduce the total dose of opioids received in the first 24 hours after surgery
The purpose of this study is to determine whether transdermal lidocaine administered at the time of Cesarean delivery and for 12 hours postoperatively will reduce the total dose of opioids received. Our hypothesis is that a lidocaine patch will reduce the total dose of opioids received in the immediate 24 hours postdelivery. Secondary outcomes will include patient self-reported pain scores, patient-reported incidence of side effects, such as pruritis, development of objective complications, such as serious skin reactions (examples are acute generalized exanthematous pustolosis, Stevens-Johnson syndrome, and toxic epidermal necrolysis), hypersensitivity, nausea, and nervousness. Other outcomes collected will include length of stay, time to first rescue analgesic medication, total dose of opioids in 48 hours, use of supplemental oxygen during hospitalization, total dose of opioids during hospitalization, breastfeeding rates, both exclusive and in combination with formula use, amount of opioid prescribed at discharge and whether refills were requested or administered, rates of chronic pain at six weeks postpartum, and six week Edinburgh Depression Screen scores. Neonatal outcomes such as five-minute Apgar scores and development of adverse outcomes will also be collected.
Sponsor(s): Department of Obstetrics and Gynecology
My Roles: PI, mentoring Dr. Melissa Meyer, OB Resident Physician
Research Focus: To measure the total MME administered inpatient following cesarean birth.
The purpose of this study is to measure the morphine milligram equivalents (MME) dose of opioids used post-cesarean birth pre and post implementation of a standardized postoperative order set.
Research Focus: The purpose of this study is to measure the composite rate of respiratory events among post-Cesarean patients and to measure the effect of obesity (by body mass index class) and opioids on such respiratory events.
My Roles: PI, collaborating with Nicholas Schmuhl and Corrine Voils
Research Focus: Qualitative Obstetric Obesity Quality Improvement Initiative
The purpose of this intervention is to query women with obesity about their perspectives, preferences, and experiences with prenatal care, query preferred terminology, and also to seek input on potential programs that could be developed to facilitate a healthy pregnancy.
My Roles: PI
Research Focus: The purpose of this project is to determine whether our patients who receive bupivacaine injections in their Cesarean incision have improved pain or less opioid use after Cesarean delivery.
Cesarean birth is the most common major surgical procedure performed in the United States, with rate of about 31.9% of deliveries. Pain management following cesarean birth involves a combination of opioid and non-opioid analgesia. Prescription opioid abuse and dependence has increased rapidly in the United States over the past two decades, with a four-fold increased rate of unintentional overdose using prescription opioids from 2000-2010. An evaluation by the Centers for Disease Control and Prevention found that patients can indeed become addicted to opioids following treatment of acute pain, including after Cesarean birth.
The literature on the benefits of local incisional injections of local anesthetic and analgesic agents suggests it may be beneficial. Lidocaine injection at the incision site has been studied, but with and without epinephrine, with subsequent reduction in both post-cesarean opioid use and reduced post-cesarean pain. Bupivacaine has been less well studied with some studies suggesting that it is effective at reducing post-cesarean pain and others suggesting it is not.
A small number of obstetricians at UPH-Meriter currently attempt to decrease postpartum opioid use and pain by injecting bupivacaine into the Cesarean incision site. This is not a universal practice. Therefore, this project would consist of performing a chart review to determine which patients did or did not receive the exposure (injection of bupivacaine into the cesarean incision site) to determine whether this impacted the primary or secondary outcome, which would be opioid consumption and pain scores, respectively.
My Roles: PI
Research Focus: The purpose of this project is to determine whether our patients with penicillin allergy have a higher risk of developing a surgical site infection that those who do not. If so, this would imply that penicillin allergy is contributing to surgical site infections. If there is a difference, this would prompt the surgical site infection committee to potentially change our approach to antibiotic prophylaxis in women with penicillin allergy who are undergoing Cesarean delivery.
Penicillin allergy is reported in 10-20% of the population, and most patients reporting penicillin allergy receive second-line surgical site infection prophylaxis, which are typically less effective. Cesarean delivery is the second most common surgical procedure in the United States, and carries a high risk of surgical site infection. However, no prior published studies have queried whether penicillin allergy increases this risk. For the past several quarters and years, Meriter Hospital’s rate of surgical site infection has exceeded the expected rate, and efforts to reduce this rate are ongoing.
Sponsor(s): Department of Obstetrics and Gynecology
My Roles: PI, mentoring Dr. John Poehlmann, resident physician
Research Focus: In this study, we propose to evaluate the interaction between pre-existing anxiety via a pre-existing diagnosed anxiety disorder listed in the medical history, and postpartum pain control, via both self-reported pain scores in the first 24 hours after delivery and total opioid dose in the first 24 hours after delivery among women who underwent Cesarean delivery. We will also assess whether the indications for Cesarean delivery impacted postpartum pain and opioid use.
Medical Student Obesity elective
2019 - Present
Role - Preceptor
The American College of Obstetricians and Gynecologists held the Annual Clinical and Scientific Meeting in San Diego May 6-8, 2022. Faculty, fellows and residents in the UW Department of Ob-Gyn brought many exciting presentations and projects to the conference. Read more about some of their awesome accomplishments:
Division of Academic Specialists in Ob-Gyn Director Makeba Williams, MD gave the Morton and Diane Stenchever Lecture “The Women’s Health Initiative: Controversy, Confusion, Consensus” at the opening of the day on May 8:
“In 2022, is hormone therapy safe? Have we reached a point of consensus? The Women’s Health Initiative hormone therapy trial preliminary results were released summer 2002, completely altering the practice of prescribing hormone therapy to midlife and menopausal women. Controversy and confusion immediately ensued. Attend this thought-provoking session to better understand current recommendations, management strategies and treatment options for menopausal patients.”
Division of Gynecologic Oncology Director Stephen Rose, MD, presented “A Revised Markov Model Evaluating Oophorectomy at the Time of Hysterectomy for Benign Indication”, co-authored by Gynecologic Oncology Fellow Shannon Rush, MD, during a late-breaking abstracts session on May 8.
More posters and presentations:
Black Women With Low Numeracy Fare Worse in Diabetic Pregnancies - Jennifer Jacobson, MD; Amy Godecker, PhD; Jennifer Janik, MD; April Eddy, MS; Jacquelyn Adams, MD
Assessment of In-Hospital Pain Control After Childbirth and Its Correlation With Anxiety in the Postpartum Period – Clara Olson, BS; John Poehlmann, MD; Zachary Stowe, MD; Kathleen Antony, MD
Operationalizing Aspirin to Reduce Preeclampsia Risk and Related Morbidity and Mortality – Maya Gross, MD; Katherine Sampene, MD
Leveraging Quality Improvement to Promote Health Equity: Prenatal Aspirin Recommendations by Race - Maya Gross, MD; Katherine Sampene, MD
In the Eye of the Beholder: Perspectives of Fellowship Applicants on Virtual Interviews - Christine Heisler, MD
Cost-Effectiveness of Opportunistic Salpingectomy Following Vaginal Delivery for Ovarian Cancer Prevention – Matthew Wagar, MD; Makeba Williams, MD
Incredible work, all!
On the latest episode of the Women’s Healthcast, Katie Antony, MD, of the UW Ob-Gyn Division of Maternal-Fetal Medicine, discusses respectful, person-centered care, her recommendations for safe and healthy pregnancies at any weight, and concerns or considerations for pregnant people with overweight or obesity.
Listen to Healthy Pregnancy at Any Weight now!
Did you know the Women’s Healthcast is available on all your favorite podcast platforms? Whether you like to listen on Apple Podcasts, Spotify, Stitcher, Podbean, or anywhere else, you can find us! (Just search Women’s Healthcast, and while you’re at it, may as well subscribe!)
An exciting update from the UW Ob-Gyn Residency:
Our residency program was accepted into the exclusive Program Director Patient Safety and Quality (PDPQ) Educators Network partnered with the ACGME and Project ECHO.
The aim of the PDPQ Educators Network is to implement a national learning network for Program Directors (PDs) and associate Program Directors (APDs) to assist their program faculty to rapidly advance resident and fellow physician engagement in patient safety and health care quality improvement. Data from our program’s involvement will help shape the nature of QI teaching in the future for all medical specialties throughout the country.
Very happily, Katie Antony, MD, MSCI, of the UW Ob-Gyn Division of Maternal-Fetal Medicine, will serve as our site’s Team Leader. We look forward to her leadership as we continue to move the educational mission of our department Forward!
A new study published in the American Journal of Obstetrics and Gynecology-Maternal-Fetal Medicine examines the link between maternal anxiety and pain following C-section delivery.
In “The impact of preexisting maternal anxiety on pain and opioid use following cesarean delivery: a retrospective cohort study”, UW Ob-Gyn Division of Maternal-Fetal Medicine faculty Katie Antony, MD and resident John Poehlmann, MD, PGY-4 use retrospective data from C-section deliveries in 2016 and 2017 to compare average pain scores of women with and without a previous diagnosis of anxiety:
“A total of 2228 cesarean deliveries were analyzed, of which 578 (25.9%) had an anxiety disorder documented. Women with a diagnosis of anxiety had higher average pain scores (3.9 vs 3.5; P<.001) and morphine milligram equivalents use (110.4 mg vs 102.2 mg; P<.001) than women without anxiety.”
Read the whole study here!
Katie Antony, MD, of the UW Ob-Gyn Division of Maternal-Fetal Medicine, spoke with Verywell Health about COVID-19 vaccination during pregnancy!
In “COVID Vaccine During Pregnancy Protects Babies, Study Shows”, Antony provided an overview of how immunity is passed from the pregnant person to the fetus, how long antibodies persist in babies after birth, and other ways to protect newborns from COVID infections:
"Antony said that the antibodies that are passed from a pregnant person to a developing fetus do stay in the baby’s circulation after birth—but only temporarily.
“The antibodies start to decrease within the first few weeks to months of life depending on the type of antibody, how much was present, and whether there was a higher circulating amount of that antibody in the pregnant person’s blood or not,” said Antony. “Antibodies can last somewhere between a 3- to a 6-month window, but some can last up to 12 months.”"
Read the whole article here!
A new study co-authored by Katie Antony, MD, of the UW Ob-Gyn Division of Maternal-Fetal Medicine and Laura Cooney, MD, of the Division of Reproductive Endocrinology and Infertility examines whether screening for sleep apnea should be included for women seeking fertility treatment.
Published in the journal Women, “Obstructive Sleep Apnea: Another Condition to Screen for in Women with Infertility” examined questionnaire results from more than 100 women seeking fertility care in early 2021:
“In this observational study, we found that approximately 8% of young women seeking infertility evaluation screened positive for OSA using the STOP-BANG screening questionnaire. We also found that women who screened positive for OSA were also more likely to screen positive for mild depression and mild-severe anxiety.”
Read the whole study here!
Though the meeting was virtual this year, the UW Ob-Gyn Division of Maternal-Fetal Medicine brought an impressive raft of research to the Society for Maternal-Fetal Medicine’s 42nd Annual Pregnancy Meeting! Read about some of the incredible posters and presentations they shared at the conference:
Risk calculator for hypertension related postpartum readmission - Jinxin Tao, Yonatan Mintz, Ramsey Larson, Dakota Dalton, Kara Hoppe
A Spatial Approach to Examining Individual and Disparity-Level Factors and Hypertensive Disorders of Pregnancy - Erin Bailey, Maria Kamenestky, Alexa Lowry, Ronald Gangnon, Kara Hoppe
Is isolated small head circumference at 20 weeks predictive of FGR or SGA at delivery? - Brad Bosse, Madeline Wetterhahn, Erin Bailey, Janine Rhoades, J. Igor Iruretagoyena, Jacquelyn Adams
A Spatial Approach to Examining Individual and Disparity-Level Factors and Birth Outcomes - Alexa Lowry, Maria Kamenetsky, Erin Bailey, Ronald Gangnon, Kara Hoppe
Understanding endothelial dysfunction in preterm preeclampsia with severe features: utility of bedside brachial artery Doppler - Jenna Racine, Ryan Pewowaruk, Alejandro Roldan-Alzate, Ian Bird, Jason Austin, Dinesh Shah, J. Igor Iruretagoyena
Diabetes Distress Scores and Black race predicts poorer diabetes control in third trimester - Jennifer Jacobson, Amy Godecker, Jennifer Janik, April Eddy, Jacquelyn Adams
Is an isolated short femur an indication for growth ultrasounds? - Erin Bailey, Brad Bosse, Madeline Wetterhahn, J. Igor Iruretagoyena, Janine Rhoades, Jacquelyn Adams
Predicting small for gestational age infants: is it time to update the Hadlock model? - Joseph Chou, Brad Bosse, Madeline Wetterhahn, Jacquelyn Adams
Do obese women without comorbid conditions need a growth ultrasound during pregnancy? - Madeline Wetterhahn, Kathleen Antony, Brad Bosse, Jacquelyn Adams
Congratulations to all!
Katie Antony, MD, of the UW Ob-Gyn Division of Maternal-Fetal Medicine, and Melissa Meyer, MD, 2021 UW Ob-Gyn residency graduate, co-authored a new article in the Journal of Maternal-Fetal & Neonatal Medicine.
In “A standardized post-cesarean analgesia regimen reduces postpartum opioid use”, Antony and Meyer evaluated a standardized protocol of pain medications after C-section delivery. The protocol included scheduled acetaminophen and NSAIDs, with opioids for breakthrough pain. The study compared cumulative opioid use in the nine months before and nine months after the protocol was implemented. They also compared patient pain scores before and after the protocol.
Read the whole study here!
A new study by Katie Antony, MD, of the UW Ob-Gyn Division of Maternal-Fetal Medicine, was published in the Wisconsin Medical Journal. “Obstructive Sleep Apnea in Pregnancy: Early Lessons From Our Sleep Pregnancy Clinic” is eligible for continuing education credit.
In the publication, Antony and co-authors describe the prevalence of obstructive sleep apnea during pregnancy, outline interventions used in their clinic to increase the number of people completing indicated testing for sleep apnea during pregnancy, and discuss potential barriers to increasing testing.
You can read the whole publication (and complete the continuing education activity) here.
On May 13, 2021, the UW Department of Obstetrics and Gynecology hosted Department Research Day, featuring exceptional presentations on fundamental, clinical, and quality improvement research. Recorded presentations from Department Research Day are available now.
To start the morning, Kimberly Gregory, MD, MPH of Cedars-Sinai Obstetrics and Gynecology Department presented the keynote lecture “Patient Reported Outcomes in Ob/Gyn: What are they? Who Cares? And Why?”.
In the lecture, Gregory differentiated between three measures of patient outcomes, outlined types of patient-reported outcomes used in ob-gyn clinical care, and described how these measures can drive quality improvement efforts.
Other presentations at Department Research Day included:
“Bone Loss and Osteoporosis Risk in Younger Gynecologic Cancer Patients”, presented by graduating gynecologic oncology fellow Janelle Sobecki, MD, MA
“Connecting the Dots: The Role of Endothelial-Immune Interaction in the Pathophysiology of Preeclampsia”, presented by Derek Boeldt, PhD, of the Division of Reproductive Sciences
“Post-Cesarean Pain”, presented by Katie Antony, MD, of the Division of Maternal-Fetal Medicine
You can watch the lectures from Department Research Day here.
Huge congratulations to Katie Antony, MD, of the UW Ob-Gyn Division of Maternal-Fetal Medicine, who recently earned her third board certification! Antony studied for and passed the American Board of Obesity Medicine certification exam.
Over the years, Antony has worked to improve care for pregnant patients with obesity, from clinical recommendations and protocols to communication strategies for patients about obesity. In the process of preparing for the exam, Antony reports learning a lot about preferred terminology, best approaches for discussing obesity, and interventions that are effective at improving health.
“The CME classes I took to study for this and the exam were generally covered by a combination of CME funds from the department and a faculty development grant, so I wanted to express my gratitude to the department for supporting this endeavor,” Antony says.
Congratulations on this incredible achievement, Dr. Antony!
A new article in the journal BMC Pregnancy and Childbirth examines prenatal care experiences for women with obesity. Medical student Danielle Hurst is lead author on the article, with co-authors Nicholas Schmuhl, PhD, of the UW Ob-Gyn Division of Reproductive Sciences and Katie Antony, MD, of the UW Ob-Gyn Division of Maternal-Fetal Medicine.
“Prenatal care experiences among pregnant women with obesity in Wisconsin, United States: a qualitative quality improvement assessment” used interviews with women who had delivered within the last 36 months to learn about women’s experience with prenatal care, and to gauge their interest in potential prenatal education programs aimed at helping women with high BMIs have a healthy pregnancy. The article includes selected quotes from interviews with study participants, and insights gained around provider communication, patient education, and more:
“Health care teams can take steps to increase the inclusivity of clinic environments and care for pregnant women with high BMIs. This is imperative to reducing the bias and stigma experienced by this population. Ultimately, obstetric healthcare providers need to become more sensitive and confident when discussing the implications of high BMIs with women and acknowledge that women with high BMIs may have had negative experiences with healthcare providers in the past. In response to these experiences, women have found ways to initiate, advocate, and supplement their healthcare.”
Read the whole study here.
A new study published in the Wisconsin Medical Journal by UW Ob-Gyn maternal-fetal medicine fellow Jenna Racine, MD sought to survey birthing centers in Wisconsin to better understand barriers to disclosing their level of maternal care. The article was co-authored by UW-Madison Prevention Research Center Deputy Director Kate Gillespie, DNP, Cynthie Wautlet, MD, of the UW Ob-Gyn Division of Academic Specialists in Ob-Gyn, and Katie Antony, MD, of the UW Ob-Gyn Division of Maternal-Fetal Medicine.
“Birthing centers in Wisconsin need further guidance on how to complete a self-assessment of their LOMC. In order to increase self-disclosure of LOMC, statewide perinatal organizations will need to continue to emphasize the benefits of releasing this information. Organizations should also provide additional support to level 1 and 2 birthing centers and improve maternal and neonatal care overall.”
Read the whole study here!
Our congratulations to Katie Antony, MD, of the UW Ob-Gyn Division of Maternal-Fetal Medicine! The UW SMPH CHS Faculty Appointments and Promotions Committee approved Antony’s promotion to Associate Professor (CHS), effective July 1, 2021.
Antony joined the department in 2015. Please help us congratulate Dr. Antony on this exciting achievement!
Faculty, residents, fellows, researchers and more brought numerous posters and presentations to the virtual 2021 Society for Maternal-Fetal Medicine Annual Meeting at the end of January! Learn more about the wealth of research shared by our colleagues at the conference:
Racial disparities in post-operative pain experience and treatment following cesarean birth
John Poehlmann; Tiffany Green, Katie Antony, Amy Godecker
Trouble with the curve: Is an ultrasound growth curve needed to predict SGA infants?
Bradley Bosse; Jacquelyn Adams, Melissa Meyer, John Poehlmann, Janine Rhoades, Igor Iruretagoyena
Obtaining accurate blood pressures: A quality improvement initiative to increase obstetric nursing knowledge and confidence
Matt Wagar; Jacquelyn Adams, Amy Godecker, Katie Antony
Prediction of vaginal delivery utilizing intrapartum transperineal ultrasound
Stephanie Peace; Melissa Meyer, Jacquelyn Adams, Katie Antony; Luther Gaston
Comparing 32-week vs 36-week growth ultrasound for prediction of LGA infants in obese gravidae
John Poehlmann; Jacquelyn Adams, Melissa Meyer, Jenna Racine, Janine Rhoades, Igor Iruretagoyena
Impact of a Standardized Post-Cesarean Analgesia Regimen on Postpartum Opioid Use
Melissa Meyer; Katie Antony
The impact of pre-existing maternal anxiety on pain and opioid use following cesarean birth
John Poehlmann; Amy Godecker, Katie Antony
Blood pressure pattern of women with hypertensive disorders of pregnancy is highly affected by obesity
Narmin Mukhtarova (MFM research intern); Kara Hoppe co-authored
Postpartum blood pressure of Black women is significantly higher compared to non-Black women
Narmin Mukhtarova (MFM research intern); Kara Hoppe co-authored
Did institutional changes and patient behaviors surrounding COVID-19 affect perinatal outcomes?
Jenna Racine; Igor Iruretagoyena, Kara Hoppe
Distance matters. The effect of distance to the hospital on estimated blood loss.
Kara Hoppe; Alexa Lowry
Blood pressure pattern pre-pregnancy through 42-day postpartum of women with preeclampsia, gestational, and chronic hypertension
Narmin Mukhtarova (MFM research intern); Kara Hoppe
A study by Katie Antony, MD, of the UW Ob-Gyn Division of Maternal-Fetal Medicine, was published in the American Journal of Obstetrics and Gynecology – Maternal-Fetal Medicine! Jackie Adams, MD, of the MFM Division, and Laura Jacques, MD, of the Division of Academic Specialists in Ob-Gyn, co-authored the study.
“Lidocaine patches for postcesarean pain control in obese women: a pilot randomized controlled trial” assessed the impact of using lidocaine patches around cesarean incisions in patients with obesity in their overall opioid use.
The pilot study included 61 participants, who were randomized into trial or placebo group. The study assessed cumulative opioid dose within 24 hours after cesarean delivery, as well as pain and patent satisfaction:
“This pilot suggests that 5% lidocaine patches applied superior and lateral to the cesarean incision are not effective at reducing the average total dose of morphine milligram equivalents administered in the first 24 hours after cesarean delivery among women with obesity, and they did not seem to improve median pain scores. An appropriately powered randomized trial would not be expected to demonstrate reduction in opioid use or pain."
Read the whole study here!
A new article by Maternal-Fetal Medicine fellow Jennifer Jacobson, MD outlines treatment of a severe COVID-19 infection in a pregnant patient, offering insight into care for other such patients in the future.
“Use of dexamethasone, remdesivir, convalescent plasma and prone positioning in the treatment of severe COVID-19 infection in pregnancy: A case report” is online now, and will appear in the January 2021 volume of Case Reports in Women’s Health:
“Severe infection with COVID-19 virus in pregnancy offers unique management challenges for the obstetrician and critical care specialist. We report the case of a woman at 26 weeks of gestation with acute respiratory distress syndrome secondary to COVID-19 infection treated with dexamethasone, remdesivir, convalescent plasma and mechanical ventilation. Cesarean delivery was performed at 29 weeks due to worsening maternal status. This case offers insight into the assessment and successful use of treatment strategies, including dexamethasone, remdesivir, convalescent plasma, early prone positioning, conservative fluid management, permissive hypoxia and low tidal volume parameters with ventilator support for pregnancies affected by severe COVID-19 infection.”
UW Ob-Gyn MFM faculty Katie Antony, MD, Michael Beninati, MD, and Kara Hoppe, DO are co-authors on this case report. Read the whole article here. Amazing work, Dr. Jacobson!
Ted Golos, PhD, of the UW Ob-Gyn Division of Reproductive Sciences, received a Translational Basic and Clinical pilot award from the UW-Madison Institute for Clinical and Translational Research! Katie Antony, MD, of the UW Ob-Gyn Division of Maternal-Fetal Medicine, is a collaborator on the grant.
“Nonhuman Primate Placental Therapy” will build on information learned from the NICHD’s Human Placenta Project – researchers will “uniquely demonstrate the feasibility of using placenta-targeted nanoparticles with primate maternal-fetal interface specificity.”
Congratulations, Dr. Golos!