Department of
Obstetrics and Gynecology

UNIVERSITY OF WISCONSIN–MADISON
SCHOOL OF MEDICINE AND PUBLIC HEALTH
Protrait

Lisa Barroilhet, MD, MS
Associate Professor
Interim Chair

Gynecologic Oncology
UW Health



Office Address
UW Hospital and Clinics, Room: H4/638
600 Highland Ave
Madison, WI, 53705


Clinic Address
Gynecology Oncology Clinic
600 Highland Ave
Madison, WI, 53705
Phone: 608-265-1700


Administrative Assistant
Ashley Hogan
anhogan@wisc.edu
608-262-2262

Hospital Profile

Bio

Dr. Barroilhet is an Associate Professor in the department of Obstetrics and Gynecology at the University of Wisconsin School of Medicine and Public Health. She completed her four-year residency in obstetrics and gynecology at University of North Carolina-Chapel Hill. After finishing her residency in 2009, she completed her three-year clinical and research fellowship in gynecologic oncology at Brigham and Women's Hospital in Boston, Massachusetts. Dr. Barroilhet joined the University of Wisconsin Department of Obstetrics and Gynecology in 2012. She has been the recipient of the NCI Clinical Care Team Leadership Award and is currently a GOG Scholar Investigator. Most recently she has been funded by the Reproductive Science Development Program and the NCI, where she has an R01 award entitled Repurposing Atovaquone for the Prevention of Ovarian Cancer. Her primary research interests focus on prevention and early detection of ovarian cancer in a high-risk population. Dr. Barroilhet has published in numerous peer-reviewed journals and has been active in presenting research at national conferences. She has been recognized with multiple awards by her peers for exemplary teaching of residents and staff as well as patient care.


Education

BS Duke University, Durham, NC
MD University of Minnesota, Minneapolis, MN
Residency University of North Carolina, Chapel Hill, NC
Fellowship Brigham and Women's Hospital, Boston, MA
MS Clinical Investigation, University of Wisconsin - Madison , Madison, WI

Certifications

Diplomate, American Board of Obstetrics and Gynecology


Honors and Awards

UW Health Patient Experience Provider Champion Award

UW Department of Ob-Gyn John M. Anderson Award

UW Health Patient Experience Physician Champion Award

UW Health Physician Excellence Nominee

“Top Doctors”: Gynecologic Oncology,
Madison Magazine, Madison, WI


Memberships

NRG Oncology Group

Society of Gynecologic Oncology 

National Comprehensive Cancer Network

American Board of Obstetricians and Gynecologists

American Society of Clinical Oncologists


Atovaquone: An Inhibitor of Oxidative Phosphorylation as Studied in Gynecologic Cancers

Arvinder Kapur, Pooja Mehta, Aaron D Simmons, Spencer S Ericksen, Geeta Mehta, Sean P Palecek, Mildred Felder, Zach Stenerson, Amruta Nayak, Jose Maria Ayuso Dominguez, Manish Patankar, Lisa M Barroilhet

Published Date: May, 2022 - pmid:35565426 - Cancers


A phase I study of talazoparib (BMN 673) combined with carboplatin and paclitaxel in patients with advanced solid tumors (NCI9782)

Ticiana A Leal, Marina N Sharifi, Nancy Chan, Robert Wesolowski, Anita A Turk, Justine Y Bruce, Ruth M O'Regan, Jens Eickhoff, Lisa M Barroilhet, Jyoti Malhotra, Janice Mehnert, Eugenia Girda, Elizabeth Wiley, Natalie Schmitz, Shannon Andrews, Glenn Liu, Kari B Wisinski

Published Date: April, 2022 - pmid:35396812 - Cancer medicine


Ovarian Cancer Detection in Average-Risk Women: Classic- versus Nonclassic-appearing Adnexal Lesions at US

Akshya Gupta, Priyanka Jha, Timothy M Baran, Katherine E Maturen, Krupa Patel-Lippmann, Hanna M Zafar, Aya Kamaya, Neha Antil, Lisa Barroilhet, Elizabeth Sadowski

Published Date: March, 2022 - pmid:35315722 - Radiology


Racial and ethnic enrollment disparities in clinical trials of poly(ADP-ribose) polymerase inhibitors for gynecologic cancers

Matthew K Wagar, Rachel P Mojdehbakhsh, Amy Godecker, Laurel W Rice, Lisa Barroilhet

Published Date: February, 2022 - pmid:35144798 - Gynecologic oncology


Opportunistic osteoporosis screening using routine computed tomography images to identify bone loss in gynecologic cancer survivors

Janelle Sobecki, Benjamin Weigman, India Anderson-Carter, Lisa Barroilhet, Thevaa Chandereng, Mark Kliewer, Ellen Hartenbach

Published Date: February, 2022 - pmid:35101963 - International journal of gynecological cancer : official journal of the International Gynecological Cancer Society


Processing and Analysis of Ascites

Hannah M Micek, Molly J Carroll, Lisa Barroilhet, Pamela K Kreeger

Published Date: December, 2021 - pmid:34918288 - Methods in molecular biology (Clifton, N.J.)


An open-label phase I dose-escalation study of the safety and pharmacokinetics of DMUC4064A in patients with platinum-resistant ovarian cancer

Joyce Liu, Howard Burris, Judy S Wang, Lisa Barroilhet, Martin Gutierrez, Yulei Wang, Anjali Vaze, Renee Commerford, Stephanie Royer-Joo, Voleak Choeurng, Eric Humke, Kathleen Moore

Published Date: October, 2021 - pmid:34627611 - Gynecologic oncology


Identifying novel ovarian tumor biomarkers through mining of the transcriptome of circulating immune cells: A proof-of-concept study

Shitanshu Uppal, Erin Medlin, Mildred Felder, Arvinder Kapur, Robert C Sterner, Jessica Vazquez, Payton N Lindner, Aleksandar K Stanic, Lisa Barroilhet, Jesus Gonzalez-Bosquet, Manish S Patankar

Published Date: May, 2021 - pmid:34022086 - American journal of reproductive immunology (New York, N.Y. : 1989)


Ovarian Cancer, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology

Deborah K Armstrong, Ronald D Alvarez, Jamie N Bakkum-Gamez, Lisa Barroilhet, Kian Behbakht, Andrew Berchuck, Lee-May Chen, Mihaela Cristea, Maria DeRosa, Eric L Eisenhauer, David M Gershenson, Heidi J Gray, Rachel Grisham, Ardeshir Hakam, Angela Jain, Amer Karam, Gottfried E Konecny, Charles A Leath, Joyce Liu, Haider Mahdi, Lainie Martin, Daniela Matei, Michael McHale, Karen McLean, David S Miller, David M O'Malley, Sanja Percac-Lima, Elena Ratner, Steven W Remmenga, Roberto Vargas, Theresa L Werner, Emese Zsiros, Jennifer L Burns, Anita M Engh

Published Date: February, 2021 - pmid:33545690 - Journal of the National Comprehensive Cancer Network : JNCCN


Oxidative stress induced by the anti-cancer agents, plumbagin, and atovaquone, inhibits ion transport through Na+/K+-ATPase

Yousef Alharbi, Arvinder Kapur, Mildred Felder, Lisa Barroilhet, Bikash R Pattnaik, Manish S Patankar

Published Date: November, 2020 - pmid:33177587 - Scientific reports


Berzosertib plus gemcitabine versus gemcitabine alone in platinum-resistant high-grade serous ovarian cancer: a multicentre, open-label, randomised, phase 2 trial

Panagiotis A Konstantinopoulos, Su-Chun Cheng, Andrea E Wahner Hendrickson, Richard T Penson, Susan T Schumer, L Austin Doyle, Elizabeth K Lee, Elise C Kohn, Linda R Duska, Marta A Crispens, Alexander B Olawaiye, Ira S Winer, Lisa M Barroilhet, Siqing Fu, Michael T McHale, Russell J Schilder, Anniina Färkkilä, Dipanjan Chowdhury, Jennifer Curtis, Roxanne S Quinn, Brittany Bowes, Alan D D'Andrea, Geoffrey I Shapiro, Ursula A Matulonis

Published Date: June, 2020 - pmid:32553118 - The Lancet. Oncology


Identification of unique clusters of T, dendritic, and innate lymphoid cells in the peritoneal fluid of ovarian cancer patients

Jessica Vazquez, Melina Chavarria, Gladys E Lopez, Mildred A Felder, Arvinder Kapur, Antonio Romo Chavez, Nathan Karst, Lisa Barroilhet, Manish S Patankar, Aleksandar K Stanic

Published Date: June, 2020 - pmid:32524661 - American journal of reproductive immunology (New York, N.Y. : 1989)


A randomized phase II evaluation of weekly gemcitabine plus pazopanib versus weekly gemcitabine alone in the treatment of persistent or recurrent epithelial ovarian, fallopian tube or primary peritoneal carcinoma

L R Duska, G R Petroni, N Varhegyi, J Brown, D Jelovac, K N Moore, W P McGuire, C Darus, L M Barroilhet, A A Secord

Published Date: April, 2020 - pmid:32247603 - Gynecologic oncology


Comparison of International Ovarian Tumor Analysis Simple Rules to Society of Radiologists in Ultrasound Guidelines for Detection of Malignancy in Adnexal Cysts

Krupa K Patel-Lippmann, Elizabeth A Sadowski, Jessica B Robbins, Viktoriya Paroder, Lisa Barroilhet, Elizabeth Maddox, Timothy McMahon, Emmanuel Sampene, Ashish P Wasnik, Alexander D Blaty, Katherine E Maturen

Published Date: November, 2019 - pmid:31770022 - AJR. American journal of roentgenology


Anti-programmed Death-1 Immunotherapy for Endometrial Cancer with Microsatellite Instability-High Tumors

Janelle Sobecki-Rausch, Lisa Barroilhet

Published Date: November, 2019 - pmid:31754884 - Current treatment options in oncology


Dr. Barroilhet's Research Focus

Dr. Barroilhet's laboratory works on ovarian cancer prevention and early detection. Other projects include novel imaging techniques and identifying circulating biomarkers.


UW Ob-Gyn presentations at 2022 Society of Gynecologic Oncology conference

Members of the UW Ob-Gyn Division of Gynecologic Oncology, fellows and residents prepared an impressive slate of posters and presentations for the 2022 Society of Gynecologic Oncology Annual Meeting on Women’s Cancer! Take a look at just some of the research brought to the hybrid conference, as well as the variety of service and leadership roles held by members of our department:

Ahmed Al-Niaimi, MD:

Master Class: Optimize and Operate: Enhancing Perioperative Quality, Safety, Experience, and Outcomes

Master Class: Debulk and Deliver: A Virtual Live-Streamed Master Class with Optional Hands-On Cytoreductive Surgery Lab 

Oral Plenary Presentation: Mechanical bowel preparation and post-operative renal dysfunction in patients undergoing cytoreductive surgery for ovarian cancer

Lisa Barroilhet, MD, MS:

Distillation: On-Demand Oral Featured Posters: Novel Therapies, PROs, and Disparities in Care

Special Interest Session: Curriculum for Emerging Clinical Trialists (Dr. Barroilhet is course director for this session)

Vice-Chair of the Patient Education Committee

Katherine Dryer, MD:

Poster: Outpatient palliative care utilization and aggressiveness of end-of-life care in women with gynecologic cancers (authors Kathryn Dryer MD, Janelle Sobecki MD, Michael Lasarev MS, Lena Law BA, Anna Stecher MD, Ellen Hartenbach MD)

Maya Gross, MD, MPH:

Poster: Risk factors associated with distress among postoperative patients in an academic gynecologic oncology practice

Ellen Hartenbach, MD:

Symposium: Wake to Wellness: Beating Burnout Through Better Patient Communication (Hartenbach presented “Mitigating Burnout Through Effective Communication Techniques”)

Palliative Medicine Committee 

Clinical Practice Committee

David Kushner, MD:

Finance Committee

Wellness Committee (Chair)

Developed two “Wake to Wellness” Sessions based on SGO Wellness Curriculum that was just published:

Managing Priorities 

Moving from Surviving to Thriving (Kushner will present as part of this session)

Senior author on Surgical Innovation presentation “Beneath the Surface: Fluorescein mapping in vulvar Paget’s Disease” given by Gyn Onc fellow Catherine Zhang, MD

Joanne Rash, PA:

Attending the SGO Board meeting (virtually), and will start her board term as the first-ever APP representative on the SGO board

Stephen Rose, MD:

Co-Chair of the Fellowship Program Directors Network and will be leading the annual meeting Thursday night. 

Hosting the UW Fellow Alumni Reception Sunday night

Senior author on Connor Wang’s study: Adaptive and maladaptive humor styles are closely associated with burnout and professional fulfillment in members of the Society of Gynecologic Oncology

Shannon Rush, MD:

Poster: Hormone replacement therapy counseling at prophylactic bilateral salpingo-oophorectomy in high risk patients

Janelle Sobecki, MD:

Poster: Risk factors associated with distress among postoperative patients in an academic gynecologic oncology practice (Maya Gross, Sumer Wallace - Senior)

Poster: Outpatient Palliative Care Utilization and Aggressiveness of End-of-Life Care in Women with Gynecologic Cancers (Kathryn Dryer, Ellen Hartenbach – Senior)

Sumer Wallace, MD:

Serves on Policy, Quality, & Outcomes task force for the Health Policy and Socioeconomic committee

Connor Wang, MD:

Poster: Adaptive and maladaptive humor styles are closely associated with burnout and professional fulfillment in members of the Society of Gynecologic Oncology

Catherine Zhang, MD:

Poster: Thromboembolic events in gynecologic cancer patients treated with chemotherapy (authors R. Zhang, MD; T. Stewart, BS; K. Tetreault, MS; R. Alexandridis, PhD; J. Bergsbaken, PharmD;  S. Wallace, MD; D. Kushner, MD;E. Hartenbach, MD)

Farr Nezhat Session Surgical Innovation Session: How Surgical Futurists are Revolutionizing Cancer Care (Zhang presented “Beneath the Surface: Fluorescein mapping in vulvar Paget’s Disease”)

Congratulations to all for these incredible achievements!


Sobecki published in International Journal of Gynecologic Cancer

Janelle Sobecki, MD, of the UW Ob-Gyn Division of Gynecologic Oncology, is lead author on a new study published in the International Journal of Gynecologic Cancer!

In “Opportunistic osteoporosis screening using routine computed tomography images to identify bone loss in gynecologic cancer survivors”, Sobecki and co-authors (including gynecologic oncology faculty Lisa Barroilhet, MD, MS, Ellen Hartenbach, MD, and resident India Anderson-Carter, MD, PGY-2) examined bone loss in a retrospective cohort of people who underwent oophorectomy for gynecologic cancer. The total sample of 185 patients showed significant changes in bone mineral density over time:

“Women with gynecologic cancers may experience accelerated cancer treatment-induced bone loss. Routine CT imaging is a convenient screening modality to identify those at highest risk for osteoporosis who warrant further evaluation with dual-energy X-ray absorptiometry. Routine bone mineral density assessments 1 year following oophorectomy for cancer treatment may be warranted in this population.”

Read the whole study here.


Wagar published in Journal of Ob-Gyn Hospital Medicine

A new article in the latest issue of the Journal of Ob-Gyn Hospital Medicine looks at rates of removal of fallopian tubes during postpartum sterilization procedures.

Trends in Postpartum Opportunistic Salpingectomy During Vaginal Delivery Admissions”, by UW Ob-Gyn resident Matt Wagar, MD, PGY-4 and co-authors Amy Godecker, PhD, Maria Landeros, Lisa Barroilhet, MD MS, and Makeba Williams, MD, is a retrospective study looking at rates of bilateral salpingectomy before and after the Society of Gynecologic Oncology issued a practice statement recommending patients consider salpingectomy rather than tubal ligation to lower future cancer risk. Their comparison found:

“Patient demographics before and after January 1st, 2014, did not significantly differ between the time periods. In 2014, 5.9% of sterilization procedures were completed as salpingectomies, increasing to 80% by 2019 (p-value for trend <0.001). No differences in postoperative complications or readmissions were noted between the two time periods.”

Read the whole study here!


Wagar published in Gynecologic Oncology

A new article in the journal Gynecologic Oncology by UW Ob-Gyn resident Matt Wagar, MD, PGY-4 examines whether enrollments in clinical trials for PARP inhibitors reflects the racial and ethnic diversity of people who are diagnosed with ovarian cancer.

Racial and ethnic enrollment disparities in clinical trials of poly(ADP-ribose) polymerase inhibitors for gynecologic cancers”, by Wagar and co-authors Rachel Mojdehbakhsh, MD, Amy Godecker, PhD, Laurel Rice, MD, and Lisa Barroilhet, MD, is a retrospective review utilizing data from 15 PARP inhibitor trials on ClinicalTrials.gov. The study found:

“[Non-Hispanic] NH-Black and Hispanic patients are significantly underrepresented in clinical trials evaluating PARP inhibitors for ovarian cancers compared to NH-White cohorts. Phase II/III trials assessing PARP inhibitors for ovarian cancers do not accurately represent the populations diagnosed with these malignancies. Enrollment strategies are needed to increase diversity in PARP inhibitor clinical trials for women's cancers.”

Read the whole study here!


Barroilhet joins ICTR Graduate Program in Clinical Investigation admissions committee

Lisa Barroilhet, MD, of the UW Ob-Gyn Division of Gynecologic Oncology, was recently invited to join the UW-Madison Institute for Clinical and Translational Research’s admissions and recruiting subcommittee for the Graduate Program in Clinical Investigation! Her three-year term began on January 1, 2022.

The admissions and recruiting subcommittee makes final, program-level decisions about admissions of new PhD and MS students, as well as evaluates transfer requests into the program from UW-Madison students.

Congratulations, Dr. Barroilhet!


Barroilhet discusses patient education with Health Professional Radio

On a recent episode of Health Professional Radio, Lisa Barroilhet, MD of the UW Ob-Gyn Division of Gynecologic Oncology, discussed the launch of the Foundation for Women’s Cancer #MoveTheMessage campaign.

In the interview, Barroilhet talked about the need for greater awareness of gynecologic cancers, the importance of having accessible, inclusive education materials readily available for patients and providers, and why increased research funding is crucial for improving gynecologic cancer outcomes. She also outlined the new #MoveTheMessage campaign from the Foundation for Women’s Cancer, a campaign focused on sharing free, inclusive educational materials about several aspects of gynecologic cancer – signs and symptoms, treatments, clinical research, and more.

Listen to Dr. Barroilhet’s whole interview here!


Barroilhet promoted to Associate Professor (tenure track)

Our congratulations to Lisa Barroilhet, MD, of the UW Ob-Gyn Division of Gynecologic Oncology! Barroilhet has been promoted to Associate Professor (Tenure Track). The promotion and track transfer will be effective July 1, 2021. Previously, Barroilhet was an associate professor (CHS track).

Since joining the department in 2012, Barroilhet has earned a distinguished reputation in research and patient care. Just a few incredible accomplishments in recent years: in 2020, she earned an R01 grant from the NIH to study atovaquone and ovarian cancer, and was appointed the first-ever Dolores A. Buchler, MD Professor of Gynecologic Oncology

Congratulations, Dr. Barroihet!


Grand Rounds: Badger Bytes on opioids and women’s health

On Thursday, January 7, a multidisciplinary group presented Badger Bytes Grand Rounds lectures as part of the presentation “The Multiple Dimensions of Opioid Use for Women’s Health.” The session was moderated by UW Ob-Gyn Division of Reproductive and Population Health Director Deborah Ehrenthal, MD, MPH.

Erin Nacev, MD/MPH student in the UW SMPH started off with “Prenatal Opioid Use Disorder and Birth Outcomes in Wisconsin". In her presentation, Nacev examined the prevalence of prenatal opioid use disorder and uptake of medication-assisted treatment among Medicaid-covered births in Wisconsin, and discussed future directions for research on OUD and pregnancy.

Next, UW Ob-Gyn resident Emily Buttigieg, MD, PGY-4 presented "Gynecologic Surgery Postoperative Narcotic Use". In the presentation, Buttigieg examined prescribing patterns for opioids after gynecologic surgery at a large academic medical center, and estimated ideal prescription size to reduce unused opioids after procedures.

Lisa Barroilhet, MD, of the UW Ob-Gyn Division of Gynecologic Oncology presented the last lecture “Opioids, Cancer and the Immune System: Untangling a Complicated Relationship". Barroilhet outlined some ways opioids affect cancer treatments, options for pain control while limiting opioids, and areas for further study.

Watch the whole Badger Bytes presentation here!


First HAGO Conference was a great success!

On September 10-11, the UW Ob-Gyn Division of Gynecologic Oncology hosted the first-ever Heartland Association of Gynecologic Oncology (HAGO) meeting. More than 70 gynecologic oncology professionals tuned in for the virtual conference, which included two keynote presentations and 21 research abstract presentations.

HAGO was founded in 2020 by UW Ob-Gyn Division of Gyn Onc Director Stephen Rose, MD, and the program committee included Ryan Spencer, MD and UW Ob-Gyn Gyn Onc fellowship graduates Andrea O’Shea, MD and Shitanshu Uppal, MD.

Of the 21 abstracts selected for presentation, five were from our department (Matthew Wagar, MD with mentor Sumer Wallace, MDWagar with mentor Makeba Williams, MDShannon Rush, MD with mentor Steve Rose, MDRachel Mojdehbakhsh, MD with mentor Ryan Spencer, MD; and Connor Wang, MD with mentor Spencer).

UW Ob-Gyn Gyn Onc fellow Shannon Rush, MD earned the first Award for Clinical Research for her abstract “65 Revisited: A Revised Markov Model for Evaluating Oophorectomy at the Time of Hysterectomy for Benign Disease”!

Lisa Barroilhet, MD was also an invited distillation presenter and UW Ob-Gyn Department Chair Laurel Rice, MD gave a keynote address and received the inaugural HAGO Award for Service and Leadership.

Our congratulations to everyone involved in planning and preparing the HAGO Conference – incredible work!


Barroilhet named first-ever Dolores A. Buchler, MD, Professor in Gynecologic Oncology

A special congratulations to Lisa Barroilhet, MD, of the UW Ob-Gyn Division of Gynecologic Oncology, as she is officially appointed the first Dolores A. Buchler, MD Professor of Gynecologic Oncology. 

It is only once or twice a lifetime that you come across a doctor like Dolores “Dee” Buchler. 

Dee joined the University of Wisconsin in 1969 after finishing her residency at University of Kansas where she trained in Ob-Gyn and the emerging fields of gynecologic oncology and radiation oncology—an extremely rare combination, and especially notable for a woman at that time.  Her prowess in radiation techniques and her unparalleled surgical skills combined were truly a rare commodity.  She was a pioneer in the treatment of gynecologic malignancies and a true innovator in the field, developing techniques for women’s cancers which now serve as the national model. 

Dee also was a leader in the department, beloved by learners, patients and colleagues alike. Dr. Buchler retired in 1995 as a professor in both Obstetrics and Gynecology and Human Oncology, leaving behind a legacy of impactful education, innovation, and care. 

In 2015, Dee established the Dolores Buchler Faculty Fellowship of Gynecologic Oncology to support a young surgeon with a passion for research and educating a new generation of doctors.  This year, Dee doubled down on her legacy by transforming her Fellowship to a Professorship, taking advantage of a unique match opportunity provided by John and Tashia Morgridge.

We are thrilled to add Dr. Lisa Barroilhet, the Dolores A. Buchler Professor of Gynecologic Oncology, to our growing list of endowed professors in Obstetrics and Gynecology. The funding provided by Dr. Buchler will protect Dr. Barroilhet’s time and provide discretionary funding to advance her research.

Dr. Buchler’s generosity and vision continue to inspire our department and work, and we will be forever grateful as her professorship moves the needle on women’s cancers forever. 

To learn more about professorships and endowed funds to support Ob-Gyn research, faculty, and training, contact Lily Johnson at 608-354-4918 or lily.johnson@supportuw.org